LPhD136 Advanced methods in glycobiology

Details
Responsible DepartmentDepartment of Plant Biology and Biotechnology   60 %
Department of Food Science   25 %
Department of Human Nutrition   15 %

Research SchoolBiotechnology (FOBI)
 
Course DatesIntroduction lecture: Tueaday 20th of November. The course will follow the block 2.A. structure. Start: Tuesday 20th of November. End: Thursday 20th of December. Report deadline: 6th of January 2013
 
Course AbstractThe course will provide hands-on experience in selected techniques for the analysis of complex carbohydrates including: state-of-the-art carbohydrate microarrays; monoclonal antibodies; carbohydrate binding modules; immunocytochemistry; rheology; spectroscopy and carbohydrate-active enzyme assays. The aim of the course is to provide participants with the skills needed to apply these techniques to their own research.
 
Course RegistrationTo sign up for the course, please send an e-mail to William GT Willats (willats@life.ku.dk) and Bodil Jørgensen (boj@life.ku.dk) Please also remember to add the course to your PhD plan.
 
Deadline for Registration31st of October 2012
 
Credits2.5 (ECTS)
 
Level of CoursePhD course
 
Organisation of TeachingFrederiksberg Campus.
 
Language of InstructionEnglish
 
Restrictions10
 
Course Content
This course will provide a comprehensive understanding of plant polysaccharides through an integrated series of practical exercises. Students will also have opportunities to get hands-on practical experience with state of the art analytical techniques for polysaccharide analysis with a particular emphasis on relating structure to function and the effects of enzymatic and chemical modifications.
 
Teaching and learning Methods
Two single or double lectures a week, two weekly theoretical or practical exercises of two to six hours duration, individual preparatory work. The course is evaluated on basis of the lab reports.
 
Learning Outcome
The primary outcomes will be a sound knowledge of the biology and utilization of plant polysaccharides. After completing the course, students should be able to:
Knowledge
. Demonstrate a practical knowledge of cutting-edge techniques for polysaccharide analysis, including the construction and use of carbohydrate microarrays for high throughput screening.
. Demonstrate a detailed understanding of the use of plant polysaccharides as functional food ingredients, nutraceuticals, therapeutics and as novel bio materials.
Skills
. Apply their knowledge to critically assess scientific literature.
. Use selected techniques for polysaccharide analysis and glycobiology.
. Apply their knowledge to evaluate the outcome of polysaccharide analyses.
. Describe how fundamental polysaccharide biology is related to downstream industrial uses.
Competences
. Work independently and with scientific literature.
. Prepare and present written work
. Design experiments related to polysaccharide biology and applications
 
Course Literature
A mixture of orginal research papers and review articles.
 
Course Material
To be announced.
 
Course Coordinator
William George Tycho Willats, willats@life.ku.dk, Department of Plant Biology and Biotechnology/Section for Plant Glycobiology, Phone: 353-33324
Bodil Jørgensen, boj@life.ku.dk, Department of Agriculture and Ecology/Plant and Soil Science, Phone: 353-33466
 
Type of Evaluation
In order to pass the course, all participants must hand in a report of the lab work at the end of the course.
 
Work Load
lectures1.5
preparation20
practicals23
project work20

64.5