LPhD115 Genome and Cell Biology

Details
Responsible DepartmentDepartment of Agriculture and Ecology

Course Dates3 September - 9 November 2012
 
Course AbstractTo provide the students with comprehensive knowledge of cell functions and analysis of the genetic control of these processes. The over all aim is that the students should become able to analyze and plan experiments in the subject area of genetic control of cell functions, with the help of original papers and databases.
 
Course RegistrationTo sign up for the course, please send an e-mail to Stefan Olsson at sto@life.ku.dk. Please also remember to add the course to your PhD plan'
 
Deadline for Registration3 September 2012
 
Credits10 (ECTS)
 
Level of CoursePhD course
 
Language of InstructionEnglish
 
Mandatory PrerequisitesBasic course in biochemistry, genetics or cell biology.
 
Course Content
The following areas are covered: Gene regulation, structure of genomes and their content of information, use of databases and experimental techniques for genome analysis. Gene control. Genome function. Gene and genome techniques. Membrane structure. Membrane transport. Intracellular compartments and the sorting of proteins. Signal transduction. Cell division. Cell cycle control and programmed cell death.
 
Teaching and learning Methods
Lectures. Article work: Students will read summarize and orally present a newly published larger article. Poster work: Students prepare a posters based on original articles in selected areas that are presented at the end of the course. Student lecture: Students prepare a lecture about their own area of research and present this to the parallell masters course students.
 
Learning Outcome
The aim of the course is to give the students a broad knowledge on genome and cell biology. The textbook, Molecular Biology of the Cell by Alberts et al., will form the basis for lectures and poster work. In the course basic genetic mechanisms and elements like structure of chromosomes and genomes, DNA replication, transcription, translation and gene regulation will be covered. Furthermore, the course will deal with the internal structure of cells, membrane structures and transport of small molecules over membranes, intracellular compartments, transport between intracellular vesicles, cellular communication and apoptose.

After completing the course the student should be able to:
Knowledge:
Describe the genetic and structural elements , genetic mechanisms and cellular communication of living cells
Describe mechanisms involved in gene regulation in cells
Display overview of membrane structures, cellular compartments and transport of molecules between compartments.
Describe cell division, cell cyclus control and programmed cell death.

Skills:
Analyse and evaluate scientific papers, which describe cellular genetic mechanisms and structures as well as their intracellular structure, communication and transport.
Apply knowledge on the molecular biology of cells in the planning of own experiments.
Communicate know how on the structure and molecular mechanisms of living cells.

Competences:
Apply knowledge on the structure and molecular mechanisms of cells to further analyse problems within genome and cell biology.
 
Course Literature
Alberts et al.: Molecular Biology of the Cell, 5.ed.(2007), Garland. Supplemented with selected literature, including original articles, in some areas.
 
Course Coordinator
Stefan Olsson, sto@life.ku.dk, Department of Agriculture and Ecology/Section of Genetics and Microbiology, Phone: 353-32646
 
Course Fee
Free of charge for Ph.D. students under the Open Market for Postgraduate Courses inDenmark and from NOVA-partners
 
Type of Evaluation
Oral presentations and poster work. See Teaching and learning methods.
 
Work Load
lectures34
project work16
preparation154

204

 
Other Remarks
This course is arranged together with the MSc course Genome and Cell Biology (LBIK 10135). It is thus not recommended for those that have already attended this course.