| Department of Veterinary Disease Biology | |||||||||||||||
| Earliest Possible Year | MSc. 1 year | ||||||||||||||
| Duration | One block | ||||||||||||||
| Credits | 7.5 (ECTS) | ||||||||||||||
| Course Level | MSc Kurset er fælleskursus for studerende på bach. udd. Fødevarevidenskab og kand.udd. Food Science and Technology | ||||||||||||||
| Examination | Final Examination written examination Written Exam in Lecturehall No aid allowed Description of Examination: 4 hours written exam. Weight: Written exam: 100% 7-point scale, internal examiner Dates of Exam: 28 October 2009 | ||||||||||||||
| Organisation of Teaching | lectures and discussion of questions and problems | ||||||||||||||
| Block Placement | Block 1 Week Structure: A | ||||||||||||||
| Teaching Language | English | ||||||||||||||
| Optional Prerequisites | 230002 Biochemistry 1 240009 Cell Biology | ||||||||||||||
| Restrictions | None | ||||||||||||||
| Course Contents | |||||||||||||||
| This theoretical course in fundamental immunology will be both basic immunological principles and also give an updated version of molecular immunology. | |||||||||||||||
| Teaching And Learning Methods | |||||||||||||||
| Lectures, problem solving. | |||||||||||||||
| Learning Outcome | |||||||||||||||
| The objective is to provide an updated knowledge of basic cellular and molecular innate and adaptive immunology. Knowledge: Describe pathogen recognition by pattern-recognition-receptors, creation of inflammation and TLR-receptor signalling as initiators of adaptive immunity. Describe the structure and function of B-cell and T-cell receptors at the cell and protein levels, as well as the creation of the receptor repertoire at the gene level. Describe the genetics and structure of MHC molecules and the main antigen processing pathways leading to T-cell activation and effector functions. Summarise the general principles of signal transduction. Describe the development of lymphocytes and tolerance induction in primary lymphoid organs. Define the main functional differences between the most important T-cell and B-cell subsets and creation of memory. Describe the main special features of mucosal immunity. Describe and explain few fundamental techniques involved in elucidation and exploration of the immune system (i.e. hybridomas, transgenesis, knock-outs). Explain and describe main effector mechanism of immunity when an organism is challenged by various pathogens - from the onset and until clearance. Skills: Use immunologically founded reasoning on various scientific problems concerning health and related issues. Competences: Have acquired knowledge, in a non-experimental context Be able to discuss immunological literature, immunological problems Have gained an updated knowledge of basic molecular immunology. | |||||||||||||||
| Course Litterature | |||||||||||||||
| Janeway's Immunobiology by Murphy, Travers, Walport. 7th ed. 2007. chapters 1-11 | |||||||||||||||
| Course Coordinator | |||||||||||||||
| Søren Skov, sosk@life.ku.dk, Department of Veterinary Disease Biology/Section for Virology, Immunology and Fish diseases, Phone: 35333126 | |||||||||||||||
| Study Board | |||||||||||||||
| Study Committee NSN | |||||||||||||||
| Course Scope | |||||||||||||||
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