240050 Immunology - Theoretical

Detaljer
Institut for Veterinær Sygdomsbiologi
English titleImmunology - Theoretical
Tidligst mulig placeringKandidat 1.år
VarighedEn blok
 
Pointværdi7.5 (ECTS)
KursustypeKandidatkursus
Kurset er fælleskursus for studerende på bach. udd. Fødevarevidenskab og kand.udd. Food Science and Technology
 
EksamenSluteksamen

skriftlig prøve


Skriftlig auditorieeksamen

uden hjælpemidler

Beskrivelse af eksamen: 4 hours written exam.

Vægtning: Written exam: 100%



7-trinsskala, intern censur

Eksamensdatoer:
28. oktober 2009
 
Rammer for undervisninglectures and discussion of questions and problems
 
BlokplaceringBlock 1
Ugestruktur: A
 
UndervisningssprogEngelsk
 
Anbefalede forudsætninger230002 Biokemi 1
240009 Cellebiologi
 
Begrænset deltagerantalNone
 
Kursusindhold
This theoretical course in fundamental immunology will be both basic immunological principles and also give an updated version of molecular immunology.
 
Undervisningsform
Lectures, problem solving.
 
Målbeskrivelse
The objective is to provide an updated knowledge of basic cellular and molecular innate and adaptive immunology.


Knowledge:
Describe pathogen recognition by pattern-recognition-receptors, creation of inflammation and TLR-receptor signalling as initiators of adaptive immunity.
Describe the structure and function of B-cell and T-cell receptors at the cell and protein levels, as well as the creation of the receptor repertoire at the gene level.
Describe the genetics and structure of MHC molecules and the main antigen processing pathways leading to T-cell activation and effector functions.
Summarise the general principles of signal transduction.
Describe the development of lymphocytes and tolerance induction in primary lymphoid organs.
Define the main functional differences between the most important T-cell and B-cell subsets and creation of memory.
Describe the main special features of mucosal immunity.
Describe and explain few fundamental techniques involved in elucidation and exploration of the immune system (i.e. hybridomas, transgenesis, knock-outs).
Explain and describe main effector mechanism of immunity when an organism is challenged by various pathogens - from the onset and until clearance.

Skills:
Use immunologically founded reasoning on various scientific problems concerning health and related issues.


Competences:
Have acquired knowledge, in a non-experimental context
Be able to discuss immunological literature, immunological problems
Have gained an updated knowledge of basic molecular immunology.
 
Litteraturhenvisninger
Janeway's Immunobiology by Murphy, Travers, Walport. 7th ed. 2007.
chapters 1-11

 
Kursusansvarlig
Søren Skov, sosk@life.ku.dk, Institut for Veterinær Sygdomsbiologi/Faggruppen f Virologi, Immunologi og Fiskesygdomme, Tlf: 35333126
 
Studienævn
Studienævn NSN
 
Kursusbeskrivelsesomfang
forelæsninger20
teoretiske øvelser32
praktiske øvelser0
forberedelse150
eksamen4

206