| Department of Ecology
70 % Department of Plant Biology 30 % | |||||||||||||||||
| Earliest Possible Year | MSc. 1 year to MSc. 2 year | ||||||||||||||||
| Duration | One block | ||||||||||||||||
| Credits | 7.5 (ECTS) | ||||||||||||||||
| Course Level | MSc | ||||||||||||||||
| Examination | Final Examination written examination and oral examination Portfolio Examination All aids allowed Description of Examination: Written short essay on a given topic during the course. Final oral exam on a given topic within pensum. Weight: Essay 20% Oral exam 80% 7-point scale, internal examiner | ||||||||||||||||
| Requirement For Attending Exam | Lab reports handed in and short essay handed in before deadlines. | ||||||||||||||||
| Organisation of Teaching | |||||||||||||||||
| Block Placement | Block 2 Week Structure: B | ||||||||||||||||
| Teaching Language | English | ||||||||||||||||
| Areas of Competence the Course Will Address | |||||||||||||||||
| Basic Science Knowledge of fungal genomics, transcriptomics, metabolomics and phenotypes. Understanding and comprehending the information obtained by datamining and ability to extract relevant information at the theoretical level and for design of experiments. Technology and production: Knowledge of functional genomics of filamentous fungi in relation to practical problems in the biotechnological industry and in agriculture. Ability to apply, transfer and make judgment of functional genomics in the development of fungal production strains, exploitation of compounds and enzymes, and as biocontrol organisms. Ethics and values: Knowledge and understanding of ethics in relation to the exploitation of fungal functional genomics. | |||||||||||||||||
| Course Objectives | |||||||||||||||||
| Give the students an advanced understanding of fungal functional genomics including sequence, protein, metabolite and enzyme potential. Enable the students to evaluate the potential of information for exploitation in industrial ventures including strain improvement, drug leads, enzymes and biocontrol. Train the students in critical evaluation of information from sequence and protein databases and results from DNA chip based expression profiling. | |||||||||||||||||
| Course Contents | |||||||||||||||||
| The course will cover genetics, genomics and expression profiling in filamentous fungi in relation to strain improvement, identification/discovery of enzymes and bioactive compounds as well as gene regulation. Means to resolved biosynthetic pathways and determination of bioactivity and toxicological characteristics will be covered. Pathogenicity factors, toxins, hydrolytic enzymes and cellular processes such as autophagy will be discussed in relation to development of disease resistant plants. Development of fungal reporter strains for gene expression studies, infection processes, microbial interactions/biocontrol and protein tagging to localise cellular processes to compartments will also be included. Finally fungal nutrition in relation to N/C content and the fight for iron in the environment and during pathogenicity will be discussed. | |||||||||||||||||
| Teaching And Learning Methods | |||||||||||||||||
| The course consists of 50% theoretical teaching and 50% project/case work. | |||||||||||||||||
| Learning Outcome | |||||||||||||||||
| Fremgår af beskrivelsen af kursets kompetenceområder | |||||||||||||||||
| Course Litterature | |||||||||||||||||
| Reviews and original papers will be used. | |||||||||||||||||
| Course Coordinator | |||||||||||||||||
| Stefan Olsson, sto@life.ku.dk, Department of Agriculture and Ecology/Section of Genetics and Microbiology, Phone: 35332646 | |||||||||||||||||
| Study Board | |||||||||||||||||
| Study Committee NSN | |||||||||||||||||
| Course Scope | |||||||||||||||||
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