240058 Functional Genomics of Filamentous Fungi

Detaljer
Inst. for Økologi   70 %
Inst. for Plantebiologi   30 %
Tidligst mulig placeringKandidat 1.år til Kandidat 2. år
VarighedEn blok
 
Pointværdi7.5 (ECTS)
KursustypeKandidatkursus
 
EksamenSluteksamen

skriftlig og mundtlig eksamen

Portfolio eksamen


Alle hjælpemidler tilladt

Beskrivelse af eksamen: Written short essay on a given topic during the course. Final oral exam on a given topic within pensum.

Vægtning: Essay 20% Oral exam 80%



7-trinsskala, intern censur
 
Forudsætninger for indstilling til eksamenLab reports handed in and short essay handed in before deadlines.
 
Rammer for undervisning
 
BlokplaceringBlock 2
Ugestruktur: B
 
UndervisningssprogEngelsk
 
Kompetenceområder
Basic Science
Knowledge of fungal genomics, transcriptomics, metabolomics and phenotypes. Understanding and comprehending the information obtained by datamining and ability to extract relevant information at the theoretical level and for design of experiments.

Technology and production:
Knowledge of functional genomics of filamentous fungi in relation to practical problems in the biotechnological industry and in agriculture. Ability to apply, transfer and make judgment of functional genomics in the development of fungal production strains, exploitation of compounds and enzymes, and as biocontrol organisms.

Ethics and values:
Knowledge and understanding of ethics in relation to the exploitation of fungal functional genomics.
 
Kursets målsætning
Give the students an advanced understanding of fungal functional genomics including sequence, protein, metabolite and enzyme potential. Enable the students to evaluate the potential of information for exploitation in industrial ventures including strain improvement, drug leads, enzymes and biocontrol. Train the students in critical evaluation of information from sequence and protein databases and results from DNA chip based expression profiling.
 
Kursusindhold
The course will cover genetics, genomics and expression profiling in filamentous fungi in relation to strain improvement, identification/discovery of enzymes and bioactive compounds as well as gene regulation. Means to resolved biosynthetic pathways and determination of bioactivity and toxicological characteristics will be covered. Pathogenicity factors, toxins, hydrolytic enzymes and cellular processes such as autophagy will be discussed in relation to development of disease resistant plants. Development of fungal reporter strains for gene expression studies, infection processes, microbial interactions/biocontrol and protein tagging to localise cellular processes to compartments will also be included. Finally fungal nutrition in relation to N/C content and the fight for iron in the environment and during pathogenicity will be discussed.
 
Undervisningsform
The course consists of 50% theoretical teaching and 50% project/case work.
 
Målbeskrivelse
Fremgår af beskrivelsen af kursets kompetenceområder
 
Litteraturhenvisninger
Reviews and original papers will be used.
 
Kursusansvarlig
Stefan Olsson, sto@life.ku.dk, Institut for Jordbrug og Økologi/Faggruppe Genetik og Mikrobiologi, Tlf: 35332646
 
Studienævn
Studienævn NSN
 
Kursusbeskrivelsesomfang
forelæsninger32
teoretiske øvelser25
praktiske øvelser23
ekskursioner7
forberedelse100
eksamen20

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