240053 Mammalian Genomics

Details
Department of Bacic Animal and Veterinary Sciences   90 %
Department of Plant Biology   5 %
Department of Agricultural Sciences   5 %
Earliest Possible YearBSc. 3 year
DurationOne block
 
Credits7.5 (ECTS)
Course LevelJoint BSc and MSc
 
Examinationwritten examination and oral examination


All aids allowed

Description of Examination: The oral examination, is based on the theoretical case studies, on the practical laboratory work and on the textbook pages given as examination requirements

Weight: 100%



7-point scale, internal examiner
 
Organisation of TeachingLectures, theoretical and practical exercises, case work, project work
 
Block PlacementBlock 1
Week Structure: A
 
Teaching LanguageEnglish
 
Optional PrerequisitesGenetik 1, Genetik 2/pattedyr
 
Restrictions20
 
Areas of Competence the Course Will Address
Scientific:
Knowledge of the mammalian genomes. Knowledge of the possibilities of analysing and characterizing mammalian genomes. Understanding of qualitative and quantitative genetics with focus on mammalian disease genetics.

Technology and production:
Knowledge of advanced concepts of genome analysis in mammals. Use of advanced methods in molecular genetics.

Ethics and values:
Evaluation of strategies to dissect the genetics underlying inherited traits in mammals. Evaluate the practical use of genetic testing.
 
Course Objectives
The course is an advanced course in genomics with focus on mammals. Focus will be on recent advances within the field of genomics with aspects of both research and application.
 
Course Contents
The following topics will be covered in the theoretical part of the course:
Genes in Pedigrees and Population
Analyzing DNA and Gene Structure, Variation and Expression
Genome Projects and Model Organisms
Organization of the Mammalian Genome
Gene Expression
Instability of the Mammalian Genome: Mutation and DNA Repair
Tree of Life
Genetic Mapping of Mendelian Characters
Identifying Disease Genes
Mapping and Identifying Genes Conferring Susceptibility to Complex Diseases
Molecular Pathology
Cancer Genetics
Genetic Testing in Individuals and Populations
Beyond the Genome Project: Functional Genomics, Proteomics and Bioinformatics
Genetic Manipulation of Cells and Animals
Novel Approaches to Treating Disease
 
Teaching And Learning Methods
Lectures, theoretical and practical exercises, case work, project work Lectures 10 hours Journal clubs 20 hours Theoretical excises/case work 15 hours Project work 90 hours Preparation 70 hours Exam 2 hours
 
Learning Outcome
Stipulated in "Areas of Competence the Course Will Address"
 
Course Litterature
Human Molecular Genetics.Third Edition. Tom Strachan, Andrew P. Read. 11/21/2003. 696 pages.


Handouts
 
Course Coordinator
Claus Bøttcher Jørgensen, chj@life.ku.dk, Department of Basic Animal and Veternary Sciences/Genetics & Bioinformatics, Phone: 35333064
 
Study Board
Study Committee NSN
 
Course Scope
lectures10
Colloquia20
theoretical exercises15
project work90
preparation69
examination2

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