| Department of Agricultural Sciences
45 % Department of Plant Biology 45 % Department of Basic Animal and Veterinary Sciences 10 % | |||||||||||||||
| Earliest Possible Year | BSc. 3 year | ||||||||||||||
| Duration | One block | ||||||||||||||
| Credits | 7.5 (ECTS) | ||||||||||||||
| Course Level | Joint BSc and MSc | ||||||||||||||
| Examination | Final Examination written examination Written Exam in Lecturehall All aids allowed Description of Examination: A four hours written examination Weight: 100 % 7-point scale, internal examiner Dates of Exam: 02 November 2007 | ||||||||||||||
| Requirement For Attending Exam | Accepted lab reports(75 %) and oral presentation of case | ||||||||||||||
| Organisation of Teaching | Teaching includes a mix of lectures, laboratory and computer exercises complemented by cases for student groups. Laboratory work demonstrates selected key issues in plant genomics. Computer exercises demonstrate the potential of internet resources. | ||||||||||||||
| Block Placement | Block 1 Week Structure: A | ||||||||||||||
| Teaching Language | English | ||||||||||||||
| Optional Prerequisites | 240032 Organism Biology 240007 Bioinformatics 1 | ||||||||||||||
| Restrictions | None | ||||||||||||||
| Areas of Competence the Course Will Address | |||||||||||||||
| Basic science: Comprehension of integrated approaches to biological questions using genetics, physiology, biochemistry and bioinformatics to relate plant phenotypes to genotype as platforms for modelling plant metabolism at the molecular level. Integration of basic knowledge on plants to understand complex biological process using plant model systems. Applied science: Understanding of the application of molecular and genetic tools for plant improvement through molecular breeding of crops for food, fodder and production of high value crops for biomedicine, biofuel, green factories, etc. Knowledge of the basic experimental techniques used in plant genomics and molecular breeding. Ethics and values: Awareness of the ethics surrounding the use of new molecular approaches in plant biotechnology e.g in relation to biodiversity. A joint session with the corresponding course on mammalian genomics will focus on the possibilities and constraints in plant and mammalian genomics as well on selected common topics of current interest. | |||||||||||||||
| Course Objectives | |||||||||||||||
| To provide basic understanding of the structure of plant genomes and experience key techniques used for studies of genomes and molecular breeding. Focus will be on the relationship between phenotypic traits and genotypes and using the expanding information on plant genomes and RNA/DNA/protein sequences. The course begins with the genomics of the two model species, rice and Arabidopsis, and translates the principles to cultivated crops to understand the potential of genomic technology. | |||||||||||||||
| Course Contents | |||||||||||||||
| Forward and reverse genetics. Mutants including: TILLING/T-DNA/transposon/spontaneous. Genome and EST sequencing programs - why particular model organisms have been chosen. Genetic diversity of plants. Phylogenetic trees, pedigrees and dendrograms based on molecular markers and gene sequences. The structure of plant genomes. Molecular marker based maps and linkage analysis. Quantitative traits and their genetics (QTL). Comparative mapping of plant genomes and the exploitation of synteny. Functional genomics. Large gene families in plants: emphasis on cytochromes P450 and MYB transcription factors In vitro culture of plants and plant regeneration. Expression profiling (arrays). Comparative genomics. | |||||||||||||||
| Teaching And Learning Methods | |||||||||||||||
| 40 % for lectures and discussion classes. 60 % for practical exercises and advice of case studies. Students are expected to work in groups for their exercises and cases and to be able to produce short hand written and oral presentations of their results. . | |||||||||||||||
| Learning Outcome | |||||||||||||||
| Stipulated in "Areas of Competence the Course Will Address" | |||||||||||||||
| Course Litterature | |||||||||||||||
| Laboratory manuals, selected scientific publications, and text book | |||||||||||||||
| Course Coordinator | |||||||||||||||
| Sven Bode Andersen, sba@life.ku.dk, Department of Agricultural Sciences/Plant and Soil Science, Phone: 35333444 Søren Bak, bak@life.ku.dk, Department of Plant Biology and Biotechnology/Plant Biochemistry Laboratory, Phone: 35333346 | |||||||||||||||
| Study Board | |||||||||||||||
| Study Committee NSN | |||||||||||||||
| Course Scope | |||||||||||||||
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