| Inst. for Økologi
40 % Inst. for Fødevarevidenskab 20 % Inst. for Veterinær Patobiologi 20 % | |||||||||||||
| Tidligst mulig placering | Kandidat 1.år | ||||||||||||
| Varighed | En blok | ||||||||||||
| Pointværdi | 15 (ECTS) | ||||||||||||
| Kursustype | Kandidatkursus | ||||||||||||
| Eksamen | Sluteksamen skriftlig og mundtlig eksamen Portfolio eksamen Alle hjælpemidler tilladt Beskrivelse af eksamen: Individual examination based on the report, presentation of results and selected articles Vægtning: 100% oral examination 7-trinsskala, intern censur | ||||||||||||
| Forudsætninger for indstilling til eksamen | Participation in site visits and theoretical activities, submission of project report | ||||||||||||
| Rammer for undervisning | Lectures and journal provide the theoretical background. The students will carry out theoretical and practical group work on a particular problem/task in microbial microbiology. Bo Jensen, Biologisk Instittut, bidrager med 20% | ||||||||||||
| Blokplacering | Block 4 Ugestruktur: Outside schedule | ||||||||||||
| Undervisningssprog | Engelsk | ||||||||||||
| Anbefalede forudsætninger | Microbiology, Biochemistry, Genetics, Microbial interactions, Genome and cellbiology, Applied Microbiology, Filamentous fungi, friends and foes, Functional genomics of filamentous fungi | ||||||||||||
| Begrænset deltagerantal | None | ||||||||||||
| Kompetenceområder | |||||||||||||
| Competences include: Basic science: Knowledge of the different ways microorganisms can been used in biotechnology: Understanding and comprehending the basic physiology and genetics of bacteria and fungi that are relevant for their exploitation in food sciences and the medical industry. Understanding and comprehending microbial pathogenesis at the genetic and physiological level. Technology and production: Knowledge of and practical experience with techniques in molecular biology, design of laboratory protocols and safety proceedures in relation to handling and exploitation of microorganisms in biotechnology. Ability to interpret results and formulate conclusions from experiments. Ethics and values: Ability to evaluate ethical aspects in the exploitation of microbial biotechnology. Awareness and ability to tranfer knowledge and experience to practical and scientific applications of microbes in biotechnology. | |||||||||||||
| Kursets målsætning | |||||||||||||
| The course aims to give the students an understanding of the diversity and properties of microorganisms and their exploitation in industry, food production, effect on human and animal health and the environment. To give practical experience with the molecular techniques available for the study of gene structure and regulation, gene manipulation, heterologous gene expression and transformation systems. To teach design of experiments and application of relevant technology. | |||||||||||||
| Kursusindhold | |||||||||||||
| Lectures and journal club will cover physiology and genetics of bacteria and fungi in relation to use of microorganisms in biotechnology. Group projects will be carried out within the following topics: 1)Fusarium spp. are plant pathogenic fungi that produce bioactive secondary metabolites/toxins of interest to the biomedical industry. To identify drug leads and regulatory systems over-expression, knock out mutagenesis, analytical chemistry and reporter gene technology is used. 2) Pseudomonas is used for biological control. Gene expression and metabolite production is studied in the bacteria in culture and in soil/plant systems to provide information on their ability to produce inhibitory compounds and their survival in the environment. 3) Many different dairy products are made by fermentations of milk with lactic acid bacteria e.g. Lactococcus lactis. Milk often contains viruses that can kill lactic acid bacteria and mechanisms that improve the survival of Lactococcus lactis will be studied. 4) Staphylococcus aureus and Listeria monocytogenes are Gram-positive pathogenic bacteria that cause infections in humans and animals. To determine the interplay between stress tolerance and virulence, protein and gene expression will be examined in relevant mutants. 5) Proteases produced by microorganisms has different biotechnological applications. Enzymes will be purified and their ability to be used as rennet or anti-fouling agents in marine paint will be examined. | |||||||||||||
| Undervisningsform | |||||||||||||
| Lectures and journal club using state of the art articles in microbial microbiology will provide the theoretical background. Site visits to Novozymes, NovoNordisk, Danisco, Christian Hansen as well as guest lecture by industrial researchers will provide the link to the job market. The students will carry out group work on a particular problem/task in microbial microbiology. They will analyse the problem theoretically and design experiments and laboratory protocols to answer their hypotheses. The different groups will interact to develop the best methods and protocols for the project. The groups will be given the possibility to carry out and plan their own experiments. The participating institutes will be responsible for particular projects. | |||||||||||||
| Målbeskrivelse | |||||||||||||
| Stipulated in "Areas of Competence the Course Will Address" | |||||||||||||
| Litteraturhenvisninger | |||||||||||||
| Reviews and original research papers | |||||||||||||
| Kursusansvarlig | |||||||||||||
| Henriette Giese, heg@life.ku.dk, Institut for Økologi/Faggruppe Genetik og Mikrobiologi, Tlf: 35332638 | |||||||||||||
| Studienævn | |||||||||||||
| Studienævn NSN | |||||||||||||
| Kursusbeskrivelsesomfang | |||||||||||||
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