270048 From gene to function in Microbial food safety

Details
Department of Veterinary Pathobiology
Earliest Possible YearBSc. 3 year to MSc. 2 year
DurationOne block
 
Credits7.5 (ECTS)
Course LevelJoint BSc and MSc
 
ExaminationFinal Examination

written examination


All aids allowed

Description of Examination: Data collected from laboratory experiments are compiled into a report, which also contains a theoretical background and a discussion of the results.

13-point scale, internal examiner
 
Organisation of TeachingLectures, practical exercises, and colloquia.
 
Block PlacementBlock 2
Week Structure: A
 
Teaching LanguageEnglish
 
Optional Prerequisites270009 Food Microbiology
240025 Microbiology
Food microbiology (270009) or microbiology (240025)
 
Areas of Competence the Course Will Address
Basic science:
- Knowledge of pathogenic bacteria transmitted via food.
- An understanding of the genes and proteins, which contribute to the survival and growth characteristics of food borne pathogenic bacteria.
- Knowledge of gene regulatory mechanisms used by food borne pathogenic bacteria in adaptation to environments found in food.
- An understanding of the biology underlying the different ways food borne pathogenic bacteria cause illness in humans.

Applied science:
- Experience in the use of molecular methods used to study the biology of pathogenic bacteria.
- Experience in reading and communicating scientific literature.

Ethics and Values:
- Critical evaluation of molecular techniques.
 
Course Objectives
The course aims at understanding the genes and the gene regulatory mechanisms, which is central for growth and survival of food borne pathogenic bacteria as well as their ability to cause illness in humans. In addition, to provide knowledge of how and why these genes and regulatory mechanisms are important for microbial food safety.
 
Course Contents
The students will obtain knowledge of the biology of food borne pathogenic bacteria that relates to the persistence in food and ability to cause illness in humans. Focus will be on how specific genes and their expression contribute to these processes and how gene expression is controlled by regulatory mechanisms both in environments like food and during infection. In the experimental part of the course the students will use fundamental molecular techniques used to study pathogenic bacteria such as PCR, cloning, methods to study gene expression, analysis of proteins and virulence factors.
 
Teaching And Learning Methods
General lectures will introduce the topics, which are focused on in colloquia and practical exercises. Primary literature forms the basis for the colloquia, and in the practical exercises the students will be guided through key molecular techniques used in scientific literature.
 
Course Coordinator
Lone Brøndsted, lobr@life.ku.dk, Department of Veterinary Pathobiology/Section for Microbiology, Phone: 35332764
 
Study Board
Study Committee LSN
 
Course Scope
lectures10
Colloquia10
practicals60
supervision26
project work50
preparation51

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