240018 Genetics 2

Details
Department of Ecology   40 %
Forest & Landscape   40 %
Department of Plant Biology   20 %
Earliest Possible YearBSc. 1 year to MSc. 2 year
DurationHalf a block
 
Credits7.5 (ECTS)
Course LevelJoint BSc and MSc
Students with little freedom in their Bachelor course should have the chance to take the course later
 
ExaminationFinal Examination

written examination and oral examination


All aids allowed

Description of Examination: Presentation of case and oral examination

Weight: Lab report 25%, case project 25% and oral examination 50%



13-point scale, internal examiner
 
Requirement For Attending ExamSubmission of at least 75% of case and lab reports.
 
Organisation of TeachingGenetics 2 consists of 20% lectures based on textbook and 30% PBL, using original literature and notes. Students can choose one of 3 parallel practical courses, 50%.
 
Block PlacementBlock 4b
Week Structure: Outside schedule, vertical division
lab courses week 7 and 8

 
Teaching LanguageEnglish
 
Mandatory PrerequisitesGenetics 1
 
Areas of Competence the Course Will Address
Competences:
Basic science:
Knowledge, understanding and comprehension of the molecular processes that transfer the genetic information in the genomes into proteins and their phenotypic effects.
Understanding and comprehension of the principles of gene regulation and ability to transfer basic knowledge into gene technology.

Technology and production:
Theoretical and practical experience with methods in molecular genetics to be able to evaluate and make judgment of their suitability for research projects.
Understanding the genetic mechanisms that regulate the differentiation of species, populations and individuals in a population in relation to natural selection and breeding. Ability to interpret results and formulate conclusions from experiments.

Ethics and values:
Awareness and ability to discuss the use of transgenic organisms in different contexts.
 
Course Objectives
Give students an understanding of replication, gene structure, transcription, translation, gene regulation and extranuclear inheritance and ability to relate this to genetic mechanisms in evolution/selection/adaptation/breeding at the genome and DNA/RNA level. Give the students experience with molecular techniques and ability to evaluate the potential of these for research and breeding purposes. Train the students in writing lab reports and interpret results.
 
Course Contents
Lectures will cover the following topics in molecular genetics: Replication, gene structure, transcription, translation, gene regulation, extranuclear inheritance and gene technology. The theories of Darwin and Mendel will be treated in relation to present day knowledge of molecular and population genetics. Risk assessment of transgenic organisms and their usefulness in research and breeding will be discussed. Lectures will be 20%, discussion groups and PBL will be 30%.
Three different parallel practical 2 week courses will be offered to supplement the theoretical part. I: Plant biodiversity: Evolution, species differentiation and phylogeny. II: Plant and microbial gene manipulation: Microbial and plant transformation systems, reporter genes and regulation of gene expression. III: Animal Genetics II: Mammalian genome analysis, DNA cloning, DNA sequencing and gene expression. The practical course will cover 50% including a case related to the choice of course.
 
Teaching And Learning Methods
Genetics 2 consists of 20% lectures based on textbook and 30% in discussion groups, PBL, where original literature and notes will be used on selected topics. Lectures will be mainly given by teachers from IØ while discussion groups with introductory presentations will be guided by teachers from all participating institutes depending on the topic. Students can choose one of the 3 parallel practical courses depending on their particular interests and study. These courses will consist of hands on laboratory work and theory based in part on original articles related to the experimental projects. The students will work on a case within a chosen area. This will cover 50%. SL and IØ will be responsible for course I; IPB and IØ will be responsible for course II and IBHV will be responsible for course III.
 
Course Litterature
Basic course book: BL Hartl og EW Jones: Genetics-Analyses of Genes and Genomes. Publ. Jones and Barlett 6. edition, supplemented with notes and articles in connection with cases/projects.
 
Course Coordinator
Henriette Giese, heg@life.ku.dk, Department of Ecology/Section of Genetics and Microbiology, Phone: 35332638
 
Study Board
Study Committee NSN
 
Course Scope
lectures17
theoretical exercises10
project work30
practicals60
preparation89

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