220001 Physical Methods in Biology

Details
Department of Natural Sciences   50 %
Department of Food Science   50 %
Earliest Possible YearBSc. 2 year to MSc. 2 year
DurationOne block
 
Credits7.5 (ECTS)
Course LevelJoint BSc and MSc
 
ExaminationFinal Examination

written examination


Written Exam in Lecturehall

All aids allowed

Description of Examination: 4 hours written examination(final), consisting of problem solution in relation to course discussed topics. 13-point scale; All aids allowed

13-point scale, internal examiner

Dates of Exam:
27 January 2006
 
Organisation of TeachingLectures, experimental exercises, theoretical exercises. The course is not offered until 2006/2007.
 
Block PlacementBlock 2
Week Structure: B
 
Teaching LanguageEnglish
may be conducted in Danish/Swedish
 
Areas of Competence the Course Will Address
Competences obtained within basic science:

Comprehend the basic physical principles of interaction between radiation and matter.
Transfer the field of application by combining physical principles and methods with actual biological problems.
Evaluate feasibility and limitation in relation to applied methods and obtained results.
Transfer the obtained competences to courses within applied science.

Competences obtained within applied science:

Apply appropiate and relevant (bio-) physical methods in relation to biological topics and problems.
Understand new and current physical methods within e.g. (bio-)nano science.
 
Course Objectives
The aim of the course is to provide a thorough fundamental knowledge of various physical methods applied to modern biological science. Education in the nature of radiation and the mechanisms of its interaction with matter supplemented by practical instrumental demonstrations provide the basis for proposing and evaluating relevant structural, dynamic and analytical physical methods in biology.

 
Course Contents
The course comprises the following three general themes: A) Basic understanding of radiation, matter and the interaction between radiation and matter, B) Applied physical methods related to structural, dynamic, energetic and analytical information and C) Specific methods involving micro- and nano-techniques.

A. Basic: Interaction of radiation with matter; Structural, dynamic, energetic and analytical methods; Electromagnetic radiation; Particle/wave duality; Physical characterisation of matter; Electric and magnetic dipole; Refractive index; Particles: Nuclei, atoms, isotopes, ions, electrons; Quantum mechanics; Maxwell-Boltzmann distribution law; Excitation sources; Detectors; Data handling; Sampling.

B. Applied, general: Absorption, scattering and emission techniques: NMR (protein structure); X-Ray fluorescence (multi-element analysis); X-Ray diffraction (structure, dynamics); Isotope techniques, tracers and dosimetry (trace elements, genetic modification); UV- and visible absorption spectrometry (analytical); Fluorescence spectrometry (analytical); Static and dynamic light scattering (structural, dynamic); IR/NIR (identification, analytical).

C. Applied, specific: Micro- and nano techniques primarily related to structural analysis: Light microscopy; Scanning electron microscopy; Transmission electron microscopy; Atomic force microscopy; Capillary X-Ray techniques; Synchrotron radiation; EXAFS; X-Ray photo emission; X-Ray standing waves.
 
Teaching And Learning Methods
The teaching comprises: Lectures, including guest lectures, will cover the fundamental topics related to the course content parts A, B and C. Small experimental demonstrations in relation to the physical methods and the biological topics are provided. Theoretical exercises are scheduled 2 hours per week. The tripartion of the course enables a partly implementation in other courses e.g. the food technology course "Quantitative Food Spectroscopy".
 
Course Litterature
J. Laursen et al, IGV, KVL. Lecture portfolio distributed at the beginning of the course.
 
Course Coordinator
Jens Laursen, jla@life.ku.dk, Department of Natural Sciences/Biophysics, Phone: 35332303
 
Study Board
Study Committee LSN
 
Course Scope
lectures28
theoretical exercises36
preparation138
examination4

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